Anti-Granzyme B antibody
Specifications
| Product Cat#: | AB-06-2029 |
| Product type: | Primary antibody |
| Antigen: | Granzyme B |
| Immunogen: | Amino acids 1-247 representing full length granzyme B of human origin. |
| Species immunized: | Mouse |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:1000); Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 ml of cell lysate) ); Immunohistochemistry (Paraffin) (1:50-1:500); Immunofluorescence (1:50-1:500) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal (4G9) |
| Form: | Liquid |
| Buffer: | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Alternative names: | C11 antibody |
| Cathepsin G like 1 antibody | |
| Cathepsin G-like 1 antibody | |
| CCPI antibody | |
| CGL 1 antibody | |
| CGL1 antibody | |
| CSP B antibody | |
| CSPB antibody | |
| CTLA-1 antibody | |
| CTLA1 antibody | |
| CTSGL1 antibody | |
| Cytotoxic serine protease B antibody | |
| Cytotoxic T lymphocyte associated serine esterase 1 antibody | |
| Cytotoxic T lymphocyte proteinase 2 antibody | |
| Cytotoxic T-lymphocyte proteinase 2 antibody | |
| Fragmentin 2 antibody | |
| Fragmentin-2 antibody | |
| GRAB_HUMAN antibody | |
| Granzyme 2 antibody | |
| Granzyme B (granzyme 2, cytotoxic T lymphocyte associated serine esterase 1) antibody | |
| Granzyme B antibody | |
| Granzyme-2 antibody | |
| GranzymeB antibody | |
| GRB antibody | |
| Gzmb antibody | |
| Hlp antibody | |
| Human lymphocyte protein antibody | |
| Lymphocyte protease antibody | |
| Protease, serine, B antibody | |
| SECT antibody | |
| T cell serine protease 1-3E antibody |
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Target information
This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
Provider
Erpantech Laboratory
