Anti-MMP-16 antibody
Specifications
| Product Cat#: | AB-07-3262 |
| Product type: | Primary antibody |
| Antigen: | MMP-16 |
| Immunogen: | A synthetic peptide derived from human MMP-16. The exact amino-acid sequence is proprietary. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2500); Immunohistochemistry (1:50-1:80); ELISA (1:8000) |
| Reactivity: | Mouse, Rat and Human |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | PBS (without Mg2+ and Ca2+ ), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol |
| Concentration: | 1 mg/ml |
| Purity: | Antigen affinity chromatography |
| Storage: | Aliquot and freeze at -20°C. Avoid multiple freeze/thaw cycles. |
| Alternative names: | MMP-X2, MMPX2, MT-MMP 3, MT-MMP2, MT-MMP3, MT3-MMP, MT3MMP, MTMMP3, matrix metalloproteinase-16, membrane-type matrix metalloproteinase 3, membrane-type-3 matrix metalloproteinase |
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Target information
Endopeptidase that degrades various components of the extracellular matrix, such as collagen type III and fibronectin. Activates progelatinase A. Involved in the matrix remodeling of blood vessels. Isoform short cleaves fibronectin and also collagen type III, but at lower rate. It has no effect on type I, II, IV and V collagen. However, upon interaction with CSPG4, it may be involved in degradation and invasion of type I collagen by melanoma cells.
Provider
Erpantech Laboratory
