Anti-GRB2 antibody
Specifications
| Product Cat#: | AB-06-2032 |
| Product type: | Primary antibody |
| Antigen: | GRB2 |
| Immunogen: | Recombinant protein |
| Species immunized: | Mouse |
| Isotype: | IgG2b |
| Applications: | Western Blot (1:400-1:1000); Immunohistochemistry (1:100-1:200); Immunocytochemistry (1:100-1:200) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal, 11-B11 |
| Form: | Liquid |
| Buffer: | 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 2 mg/ml |
| Purity: | Protein G affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Alternative names: | Abundant SRC homology antibody |
| Adapter protein GRB2 antibody | |
| ASH antibody | |
| Ash protein antibody | |
| EGFRBP GRB2 antibody | |
| Epidermal growth factor receptor binding protein antibody | |
| Epidermal growth factor receptor binding protein GRB2 antibody | |
| GRB 2 antibody | |
| GRB2 adapter protein antibody | |
| Grb2 antibody | |
| GRB2_HUMAN antibody | |
| Grb3 3 antibody | |
| Growth factor receptor bound protein 2 antibody | |
| Growth factor receptor bound protein 3 antibody | |
| Growth factor receptor-bound protein 2 antibody | |
| HT027 antibody | |
| MST084 antibody | |
| MSTP084 antibody | |
| NCKAP2 antibody | |
| OTTHUMP00000166096 antibody | |
| OTTHUMP00000166097 antibody | |
| OTTHUMP00000166098 antibody | |
| Protein ash antibody | |
| SEM5 antibody | |
| SH2/SH3 adapter GRB2 antibody |
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Target information
Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway.
Isoform 2 does not bind to phosphorylated epidermal growth factor receptor (EGFR) but inhibits EGF-induced transactivation of a RAS-responsive element. Isoform 2 acts as a dominant negative protein over GRB2 and by suppressing proliferative signals, may trigger active programmed cell death.
Provider
Erpantech Laboratory