Anti-Perforin antibody
Specifications
| Product type: | Primary antibody |
| Antigen: | Perforin |
| Immunogen: | Recombinant protein within Human Perforin aa 300-500. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:600-1:2100); Immunocytochemistry (1:100-1:250); Immunohistochemistry (1:100-1:250); Flow Cytometry (1:100-1:150) |
| Reactivity: | Mouse, Rat and Human |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 1*TBS (pH7.4), 1%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1mg/ml |
| Purity: | Protein affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Cytolysin antibody |
| FLH2 antibody | |
| HPLH2 antibody | |
| Lymphocyte pore-forming protein antibody | |
| P1 antibody | |
| PERF_HUMAN antibody | |
| perforin 1 (pore forming protein) antibody | |
| Perforin 1 antibody | |
| Perforin-1 antibody | |
| PFP antibody | |
| PGFL antibody | |
| PIGF antibody | |
| PIGF-2 antibody | |
| PLGF antibody | |
| Pore forming protein antibody | |
| prf1 antibody | |
| SHGC-10760 antibody |
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Target information
Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Plays an important role in killing other cells that are recognized as non-self by the immune system, e.g. in transplant rejection or some forms of autoimmune disease. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes.
Provider
Erpantech Laboratory
