Anti-PDZK1 antibody
Specifications
| Product type: | Primary antibody |
| Antigen: | PDZK1 |
| Immunogen: | KLH conjugated synthetic peptide derived from human PDZK1 1-100/519 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:550-2100) |
| Reactivity: | Human, Mouse, Rat, Rabbit |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | CAP70 |
| CFTR associated protein of 70 kDa | |
| CFTR associated protein, 70-KD | |
| CFTR-associated protein of 70 kDa | |
| CLAMP | |
| D3Ertd537e | |
| Dietary Pi-regulated RNA-1 | |
| Diphor-1 | |
| mPDZK1 | |
| Na(+)/H(+) exchange regulatory cofactor NHE-RF3 | |
| Na(+)/H(+) exchanger regulatory factor 3 | |
| Na/Pi cotransporter C-terminal-associated protein 1 | |
| Na/Pi cotransporter C-terminal-associated protein | |
| NaPi Cap1 | |
| NaPi-Cap1 | |
| NaPiCap1 | |
| NHERF 3 | |
| NHERF-3 | |
| NHERF3 | |
| NHRF3_HUMAN | |
| OTTHUMP00000015572 | |
| PDZ domain containing 1 | |
| PDZ domain containing protein 1 | |
| PDZ domain-containing protein 1 | |
| PDZD1 | |
| PDZK1 | |
| Sodium hydrogen exchanger regulatory factor 3 | |
| Sodium-hydrogen exchanger regulatory factor 3 | |
| 1700023D20Rik | |
| 2610507N21Rik | |
| 4921513F16Rik | |
| AI267131 | |
| AI314638 | |
| AL022680 | |
| C terminal linking and modulating protein. |
Target information
A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity. Required for normal cell-surface expression of SCARB1. Plays a role in maintaining normal plasma cholesterol levels via its effects on SCARB1. Plays a role in the normal localization and function of the chloride-anion exchanger SLC26A6 to the plasma membrane in the brush border of the proximal tubule of the kidney. May be involved in the regulation of proximal tubular Na+-dependent inorganic phosphate cotransport therefore playing an important role in tubule function (By similarity).
Provider
Erpantech Laboratory
