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Anti-PDX1 antibody

SKU Product Brand Unit Availability Price Quantity  
AB-06-3415
Anti-PDX1 antibody
Erpan Tech In stock

Specifications        

Product type: Primary antibody
Antigen: PDX1
Immunogen: Recombinant protein
Species immunized: Rabbit
Isotype: IgG
Applications: Western Blot (1:550); Immunofluorescence(1:100-1:250); Immunocytochemistry (1:100-1:250)/ Immunohistochemistry
Reactivity: Human
Clonality (clone number): Monoclonal
Buffer: 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Concentration: 1mg/ml
Purity: Protein A affinity purified
Storage: Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles.
Alternative names: Glucose sensitive factor antibody
Glucose-sensitive factor antibody
GSF antibody
IDX 1 antibody
IDX-1 antibody
IDX1 antibody
Insulin promoter factor 1 antibody
Insulin promoter factor 1 homeodomain transcription factor antibody
Insulin upstream factor 1 antibody
IPF 1 antibody
IPF-1 antibody
IPF1 antibody
Islet/duodenum homeobox 1 antibody
Islet/duodenum homeobox-1 antibody
IUF 1 antibody
IUF-1 antibody
IUF1 antibody
MODY4 antibody
Pancreas/duodenum homeobox 1 antibody
Pancreas/duodenum homeobox protein 1 antibody
pancreatic and duodenal homeobox P antibody
PDX 1 antibody
PDX-1 antibody
PDX1 antibody
PDX1_HUMAN antibody
Somatostatin transactivating factor 1 antibody
Somatostatin-transactivating factor 1 antibody
STF 1 antibody
STF-1 antibody
STF1 antibody
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Target information

Activates insulin, somatostatin, glucokinase, islet amyloid polypeptide and glucose transporter type 2 gene transcription. Particularly involved in glucose-dependent regulation of insulin gene transcription. As part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer; the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element. Binds preferentially the DNA motif 5′-[CT]TAAT[TG]-3′. During development, specifies the early pancreatic epithelium, permitting its proliferation, branching and subsequent differentiation. At adult stage, required for maintaining the hormone-producing phenotype of the beta-cell.

Provider

Erpantech Laboratory

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